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Seladelpar lysine

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Seladelpar lysine Suppliers list
Company Name: BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Tel: +86-18600796368
Email: sales@sjar-tech.com
Products Intro: Product Name:Seladelpar Lysine Dihydrate
CAS:928821-40-3
Purity:More Than 99% Package:1g;
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427
Email: sales@conier.com
Products Intro: Product Name:Seladelpar lysine
CAS:928821-40-3
Remarks:NME250249P
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:Seladelpar lysine；MBX 8025 Lysine MBX8025 Lysine;MBX-8025 lysine dihydrate;MBX-8025 Lysine
CAS:928821-40-3
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250
Email: 1059@dideu.com
Products Intro: Product Name:Seladelpar lysine dihydrate
CAS:928821-40-3
Purity:99.00% Package:1kg;5kg;25kg;100kg Remarks:ISO 9001：2015 REACH Approved Manufacture
Company Name: Shanghai Joiny Pharmaceutical Co.,LTD
Tel: +86-13681955282 +86-13681955282;
Email: gyd@joiny-pharma.com
Products Intro: Product Name:Seladelpar lysine
CAS:928821-40-3
Purity:98% Package:25kg;

Seladelpar lysine manufacturers

  • Seladelpar lysine
  • Seladelpar lysine pictures
  • 2025-11-19
  • CAS:928821-40-3
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 1000kg
Seladelpar lysine Basic information
Product Name:Seladelpar lysine
Synonyms:Seladelpar lysine;MBX 8025 Lysine MBX8025 Lysine;MBX-8025 Lysine;MBX-8025 lysine dihydrate;{4-[2-ethoxy-3-(4-trifluoromethyl-phenoxy)-propylsulfanyl]-2-methyl-phenoxy}-ethanoic acid L-lysinate dihydrate;Seladelpar L-lysine Dihydrate;Seladelpar Lysine Dihydrate
CAS:928821-40-3
MF:C27H37F3N2O7S
MW:590.66
EINECS:
Product Categories:
Mol File:928821-40-3.mol
Seladelpar lysine Structure
Seladelpar lysine Chemical Properties
form Solid
color White to off-white
InChIKeyIOIAOZMQFNHRKR-GWSIDIDRNA-N
SMILES[C@@H](N)(C(=O)O)CCCCN.O(C1C=CC(SC[C@H](OCC)COC2C=CC(C(F)(F)F)=CC=2)=CC=1C)CC(=O)O |&1:0,17,r|
Safety Information
MSDS Information
Seladelpar lysine Usage And Synthesis
UsesSeladelpar (MBX-8025) Lysine dihydrate is the Lysine dihydrate salt form of Seladelpar (HY-19522). Seladelpar Lysine dihydrate is an orally active agonist for potent PPAR-δ, with EC50 of 2 nM. Seladelpar Lysine dihydrate shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar Lysine dihydrate can be used for the study of primary biliary cholangitis. Seladelpar Lysine dihydrate normalizes hyperglycemia, hyperinsulinemia, glucose, serum lipids and cholesterol levels, ameliorates the nonalcoholic steatohepatitis in mouse model[1][2].
IC 50PPARδ: 2 nM (EC50)
References[1] Bays HE, et al. MBX-8025, a novel peroxisome proliferator receptor-delta agonist: lipid and other metabolic effects in dyslipidemic overweight patients treated with and without atorvastatin. J Clin Endocrinol Metab. 2011 Sep;96(9):2889-97. DOI:10.1210/jc.2011-1061
[2] Haczeyni F, et al. The selective peroxisome proliferator-activated receptor-delta agonist seladelpar reverses nonalcoholic steatohepatitis pathology by abrogating lipotoxicity in diabetic obese mice. Hepatol Commun. 2017 Jul 31;1(7):663-674. DOI:10.1002/hep4.1072
Seladelpar lysine Preparation Products And Raw materials
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