N-[(1S)-1-[4-[[4-Methoxy-2-[(4-methoxyphenyl)sulfonyl]phenyl]sulfonyl]phenyl]ethyl]methanesulfonamide manufacturers
- SCH-336
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- $44.00
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2026-09-10
- CAS:447459-51-0
- Purity: 97.00%
- Supply Ability: 10g
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| | N-[(1S)-1-[4-[[4-Methoxy-2-[(4-methoxyphenyl)sulfonyl]phenyl]sulfonyl]phenyl]ethyl]methanesulfonamide Basic information |
| | N-[(1S)-1-[4-[[4-Methoxy-2-[(4-methoxyphenyl)sulfonyl]phenyl]sulfonyl]phenyl]ethyl]methanesulfonamide Chemical Properties |
| Boiling point | 756.6±70.0 °C(Predicted) | | density | 1.369±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 9.61±0.40(Predicted) | | form | Solid | | color | White to off-white |
| | N-[(1S)-1-[4-[[4-Methoxy-2-[(4-methoxyphenyl)sulfonyl]phenyl]sulfonyl]phenyl]ethyl]methanesulfonamide Usage And Synthesis |
| Uses | SCH 336 is a potent, selective, inverse and orally active CB2 agonist. SCH 336 inhibits BaF3/CB2 migration. SCH 336 significantly inhibits the migration of leukocytes in vivo. SCH 336 blocks ovalbumin-induced lung eosinophilia in mice[1]. | | in vivo | SCH 336 (0.02, 0.2, 2.0 mg/kg; i.p.) significantly inhibits the migration of leukocytes[1]. | Animal Model: | Female B6D2/F1 mice (HU210)[1] | | Dosage: | 0.02, 0.2, 2.0 mg/kg | | Administration: | I.p. | | Result: | Significantly inhibited the migration of leukocytes into the CCL2-soaked gel foam sponge. |
| | IC 50 | hCB2-R | | storage | Store at RT | | References | [1] Lunn CA, et al. A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo. J Pharmacol Exp Ther. 2006 Feb;316(2):780-8. DOI:10.1124/jpet.105.093500 |
| | N-[(1S)-1-[4-[[4-Methoxy-2-[(4-methoxyphenyl)sulfonyl]phenyl]sulfonyl]phenyl]ethyl]methanesulfonamide Preparation Products And Raw materials |
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