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Cav 2.2 blocker 1 manufacturers
- Cav 2.2 blocker 1
-
- $43.00
-
2026-07-14
- CAS:1567335-29-8
- Purity: 99.44%
- Supply Ability: 10g
- Cav 2.2 blocker 1
-
- $43.00
-
2026-07-14
- CAS:1567335-29-8
- Purity: 99.44%
- Supply Ability: 10g
|
| | Cav 2.2 blocker 1 Basic information |
| Product Name: | Cav 2.2 blocker 1 | | Synonyms: | Cav 2.2 blocker 1;1H-Pyrazole, 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-(tetrahydro-2,2,6,6-tetramethyl-2H-pyran-4-yl)-;Ca2+ channels,Inhibitor,inhibit,Cav 2.2 blocker 1,Ca channels,Calcium Channel;5-(4-Chlorophenyl)-1-(2-methoxyphenyl)-3-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)-1H-pyrazole;Cav 2.2 blocker 1, 10 mM in DMSO;Cav 2.2 blocker 1 ，S0000 | | CAS: | 1567335-29-8 | | MF: | C25H29ClN2O2 | | MW: | 424.96 | | EINECS: | | | Product Categories: | | | Mol File: | 1567335-29-8.mol |  |
| | Cav 2.2 blocker 1 Chemical Properties |
| Boiling point | 547.2±50.0 °C(Predicted) | | density | 1.16±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 20.83 mg/mL (49.02 mM) | | pka | -0.67±0.10(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | Cav 2.2 blocker 1 Usage And Synthesis |
| Uses | Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM[1]. | | References | [1] Wall MJ, et al. Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Cav 2.2) blockers for the treatment of pain. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3780-3783. DOI:10.1016/j.bmcl.2018.10.007 |
| | Cav 2.2 blocker 1 Preparation Products And Raw materials |
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