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| | DIGITALIS (3 G) Basic information |
| Product Name: | DIGITALIS (3 G) | | Synonyms: | digitalone;digitannoid;digitol;FOXGLOVE;DIGITALISLANATA;DIGITALIS (3 G);digitalin(pharmaceutical);digitalis,naturalproducts,pharmaceutical | | CAS: | 8031-42-3 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![DIGITALIS (3 G) Structure]() |
| | DIGITALIS (3 G) Chemical Properties |
| WGK Germany | WGK 3 | | HS Code | 2938900000 | | Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | | Hazard Classifications | Acute Tox. 2 Oral |
| | DIGITALIS (3 G) Usage And Synthesis |
| Uses | Digitalis USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. | | Biological Functions | Lanatoside A is composed of the aglycone digitoxigenin (genin indicates no sugar) connected to
three digitoxose sugar molecules, the third of which carries a 3-acetyl group, and a terminal glucose
molecule. In other words, the structure sequence is glucose4-3-acetyldigitoxose3-digitoxose2-
digitoxose1-digitoxigenin.
Lanatoside B has the identical sugar portion to lanatoside A, except that the aglycone has extra
hydroxyl group at C-16 and is given the name gitoxigenin. The structural sequence is glucose4-3-
acetyldigitoxose3-digitoxose2-digitoxose1-gitoxigenin.
Lanatoside C also has the same sugars found in both lanatosides A and B; however, the aglycone
has the nucleus of lanatoside A plus an additional hydroxyl group at C-12. This cardenolide is
named digoxigenin. The structural sequence is glucose4-3-acetyldigitoxose3-digitoxose2-digitoxose1-
digoxigenin.
Partial hydrolysis of the glucose molecule and the acetate group from lanatoside A and C produces,
respectively, two new and most important cardiac glycosides, digitoxin and digoxin, with the
following sequences: digitoxin, (digitoxose)3-digitoxigenin; and digoxin, (digitoxose)3-digoxigenin. |
| | DIGITALIS (3 G) Preparation Products And Raw materials |
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