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| | ANHYDROERYTHROMYCIN A Basic information |
| Product Name: | ANHYDROERYTHROMYCIN A | | Synonyms: | Erythromycin EP Impurity D/Anhydroerythromycin A/(1S,2R,3R,4S,5R,8R,9S,10S,11R,12R,14R)-9-
[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-Lribo-hexopyranosyl)oxy]-5-ethyl-3-hydroxy-
2,4,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-
(dimethylamino)-β-D-xylo-hexopyra;6,9,12-Anhydroerythromycin A;9-Deoxo-6,12-dideoxy-6,9:9,12-diepoxy-erythromycin;Anhydroerythromycin;BRL 46355ER;EM 202;Erythromycin Anhydride, Impurity D;ANHYDROERYTHROMYCIN A | | CAS: | 23893-13-2 | | MF: | C37H65NO12 | | MW: | 715.91 | | EINECS: | | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 23893-13-2.mol |  |
| | ANHYDROERYTHROMYCIN A Chemical Properties |
| Melting point | 125-127°C | | Boiling point | 787.2±60.0 °C(Predicted) | | density | 1.21±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | Chloroform (Slightly), Methanol (Sparingly) | | pka | 13.46±0.70(Predicted) | | color | White to Pale Yellow | | Major Application | forensics and toxicology
pharmaceutical (small molecule) | | InChIKey | YKAVHPRGGAUFDN-JTQLBUQXSA-N | | SMILES | CC[C@H]1OC(=O)[C@H](C)[C@@H](OC2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@@]4(C)C[C@@H](C)C5(O4)OC1(C)[C@H](O)[C@H]5C | | EPA Substance Registry System | Erythromycin, 9-deoxo-6,12-dideoxy-6,9:9,12-diepoxy- (23893-13-2) |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | ANHYDROERYTHROMYCIN A Usage And Synthesis |
| Chemical Properties | Off-White to Pale Yellow Solid | | Uses | Anhydroerythromycin A is a degradation product of erythromycin formed by a complex internal rearrangement of erythromycin A on exposure to acidic conditions. In acid, erythromycin A forms the enol ether and then undergoes a second internal cyclisation of the C12–OH and C9 enol to afford the ketal, anhydroerythromycin A. Anhydroerythromycin A is an important analytical standard for erythromycin A stability studies. | | IC 50 | Macrolide |
| | ANHYDROERYTHROMYCIN A Preparation Products And Raw materials |
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