| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
|
| | P-gp modulator 1 Basic information |
| Product Name: | P-gp modulator 1 | | Synonyms: | P-gp modulator 1;Carbamic acid, N-[6-[[(3β,12β,20S,24R)-20,24-epoxy-12,25-dihydroxydammaran-3-yl]amino]-6-oxohexyl]-, 1,1-dimethylethyl ester;P gp modulator 1,Pgp modulator 1 | | CAS: | 2249749-39-9 | | MF: | C41H72N2O6 | | MW: | 689.02 | | EINECS: | | | Product Categories: | | | Mol File: | 2249749-39-9.mol |  |
| | P-gp modulator 1 Chemical Properties |
| Boiling point | 769.3±60.0 °C(Predicted) | | density | 1.10±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 12.90±0.46(Predicted) |
| | P-gp modulator 1 Usage And Synthesis |
| Uses | P-gp modulator 1 is a high affinity, orally available modulator of P-glycoprotein (Pgp), can reverse the Pgp-mediated multidrug resistance ((MDR)[1]. | | References | [1] Ren Q, et al. Design, synthesis, and discovery of ocotillol-type amide derivatives as orally available modulators of P-glycoprotein-mediated multidrug resistance. Eur J Med Chem. 2019 Jan 1;161:118-130. DOI:10.1016/j.ejmech.2018.10.038 |
| | P-gp modulator 1 Preparation Products And Raw materials |
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