| Company Name: |
Changzhou Hopschain Chemical Co.,Ltd.
|
| Tel: |
0519-85528066 13775048983 |
| Email: |
sales@hopschem.com |
| Products Intro: |
Product Name:(E)-cyclooct-4-enol / axial - TCO4 / A
CAS:39637-78-0
Purity:95% Package:1mg;10mg;100mg;1g
|
| Company Name: |
Vicbio Biotechnology Co., Ltd.
|
| Tel: |
400-001-2615 13691409741 |
| Email: |
info@vicbio.com |
| Products Intro: |
Product Name:(E)-cyclooct-4-enol / axial - TCO4 / A
CAS:39637-78-0
Purity:> 95% (HPLC-UV) Package:100mg;1000mg
|
|
| | (E)-cyclooct-4-enol / axial - TCO4 / A Basic information |
| | (E)-cyclooct-4-enol / axial - TCO4 / A Chemical Properties |
| Boiling point | 202.2±29.0 °C(Predicted) | | density | 0.954±0.06 g/cm3(Predicted) | | pka | 15.13±0.20(Predicted) |
| | (E)-cyclooct-4-enol / axial - TCO4 / A Usage And Synthesis |
| Uses | (R)-TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. (R)-TCO-OH is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. | | IC 50 | Alkyl-Chain | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | (E)-cyclooct-4-enol / axial - TCO4 / A Preparation Products And Raw materials |
|