|
|
| | 3-(Pyrrolidin-1-ylmethyl)benzoic acid hydrochloride Basic information |
| | 3-(Pyrrolidin-1-ylmethyl)benzoic acid hydrochloride Chemical Properties |
| Melting point | 168 °C | | storage temp. | Inert atmosphere,Room Temperature |
| Risk Statements | 41 | | Safety Statements | 26-39 |
| | 3-(Pyrrolidin-1-ylmethyl)benzoic acid hydrochloride Usage And Synthesis |
| Synthesis | Methyl 3-(1-pyrrolidinylmethyl)benzoate (800 mg, 3.6 mmol) was used as a raw material and dissolved in 25% aqueous hydrochloric acid (15 mL). The reaction mixture was stirred at 90 °C for 4 hours. Upon completion of the reaction, the solvent was removed by evaporation to afford 3-(1-pyrrolidinylmethyl)benzoic acid hydrochloride as a brown oil in quantitative yield. The resulting product was used directly in the subsequent reaction without further purification. | | References | [1] Patent: WO2007/68637, 2007, A1. Location in patent: Page/Page column 50 |
| | 3-(Pyrrolidin-1-ylmethyl)benzoic acid hydrochloride Preparation Products And Raw materials |
|