Pentanoic acid, 4-methyl-4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester

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Pentanoic acid, 4-methyl-4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester Basic information
Product Name:Pentanoic acid, 4-methyl-4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester
Synonyms:Pentanoic acid, 4-methyl-4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester;NO2-SPDMV-sulfo;1-(4-methyl-4-((5-nitropyridin-2-yl)disulfanyl)pentanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid;1-((4-methyl-4-((5-nitropyridin-2-yl)disulfaneyl)pentanoyl)oxy)-2,5-dioxopyrrolidine-3-sulfonic acid
CAS:663599-00-6
MF:C15H17N3O9S3
MW:479.51
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Mol File:663599-00-6.mol
Pentanoic acid, 4-methyl-4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester Structure
Pentanoic acid, 4-methyl-4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester Chemical Properties
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MSDS Information
Pentanoic acid, 4-methyl-4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester Usage And Synthesis
UsesNO2-SPDMV-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
IC 50Disulfide Cleavable Linker; Cleavable Linker
References[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
Pentanoic acid, 4-methyl-4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester Preparation Products And Raw materials
Tag:Pentanoic acid, 4-methyl-4-[(5-nitro-2-pyridinyl)dithio]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester(663599-00-6) Related Product Information
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