1H-Pyrrole-2,5-dione, 1-(5-hydroxypentyl) manufacturers
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| | 1H-Pyrrole-2,5-dione, 1-(5-hydroxypentyl) Basic information |
| | 1H-Pyrrole-2,5-dione, 1-(5-hydroxypentyl) Chemical Properties |
| Boiling point | 336.2±25.0 °C(Predicted) | | density | 1+-.0.06 g/cm3(Predicted) | | form | Oil | | pka | 15.14±0.10(Predicted) | | color | Colorless to light yellow |
| | 1H-Pyrrole-2,5-dione, 1-(5-hydroxypentyl) Usage And Synthesis |
| Uses | N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) )[1]. | | IC 50 | Non-cleavable Linker | | References | [1] Finniss, M. C., et al. A versatile acid-labile linker for antibody–drug conjugates. Med. Chem. Commun., 2014, 5(9), 1355-1358. |
| | 1H-Pyrrole-2,5-dione, 1-(5-hydroxypentyl) Preparation Products And Raw materials |
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