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| | N-Methyl protoporphyrin IX Basic information |
| Product Name: | N-Methyl protoporphyrin IX | | Synonyms: | 7,12-Diethenyl-3,8,13,17,23-pentamethyl-21H,23H-porphine-2,18-dipropanoic acid;Aids006240;Aids-006240;21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17,23-pentamethyl-;N-Methyl protoporphyrin IX | | CAS: | 79236-56-9 | | MF: | C35H36N4O4 | | MW: | 576.68 | | EINECS: | | | Product Categories: | Natural Porphyrins and Derivitives;Porphyrins | | Mol File: | 79236-56-9.mol |  |
| | N-Methyl protoporphyrin IX Chemical Properties |
| solubility | DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:5): 0.17 mg/ml; DMSO: 15 mg/ml | | form | A crystalline solid | | color | Brown to black |
| | N-Methyl protoporphyrin IX Usage And Synthesis |
| Description | N-methyl Protoporphyrin IX is a transition state analog that potently inhibits protoporphyrin IX ferrochelatase (Ki = 10 nM), blocking the terminal step of the heme biosynthetic pathway. It is used to study the effect of heme synthesis blockade in cell systems. | | Uses | N-Methylprotoporphyrin IX is a potent inhibitor of ferrochelatase enzyme[1]. | | References | [1] Ortiz de Montellano PR, et al. Inhibition of hepatic ferrochelatase by the four isomers of N-methylprotoporphyrin IX. Biochem Biophys Res Commun. 1980;97(4):1436-1442. DOI:10.1016/s0006-291x(80)80026-x |
| | N-Methyl protoporphyrin IX Preparation Products And Raw materials |
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