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| | Dopi-4,5-P2 (Na+ salt) Basic information |
| Product Name: | Dopi-4,5-P2 (Na+ salt) | | Synonyms: | 1-(1,2R-DIOCTANOYLPHOSPHATIDYL)INOSITOL-4,5-BIPHOSPHATE, PENTASODIUM SALT;PI-4,5-P2 DIOCTANOYL (NA+ SALT);PHOSPHATIDYLINOSITOL-BIS-4,5-PHOSPHATE, DIOCTANOYL, (NA+ SALT);PHOSPHATIDYLINOSITOL-4,5-DIPHOSPHATE C-8 SODIUM SALT;PTDINS-(4,5)-P2 (1,2-DIOCTANOYL) SODIUM SALT;Dopi-4,5-P2 (Na+ salt) | | CAS: | | | MF: | C25H44Na5O19P3 | | MW: | 856.48 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | Dopi-4,5-P2 (Na+ salt) Chemical Properties |
| solubility | CHCl3:CH3OH:H2O (3:2:1): 10 mg/mlPBS (pH 7.2): Freely soluble |
| | Dopi-4,5-P2 (Na+ salt) Usage And Synthesis |
| Description | The phosphatidylinositol (PtdIns) represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.1,2 PtdIns is phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2; PIP2) and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PIP2 by PI-specific phospholipase C generates IP3 and diacylglycerol (DAG). The DAG and IP3 produced by this reaction are part of a complex biochemical and signal transduction cascade that is at the frontier of scientific research today.WARNING This product is not for human or veterinary use. | | References | [1] EDUARDO G. LAPETINA P. C M M Billah. The phosphatidylinositol cycle and the regulation of arachidonic acid production[J]. Nature, 1981, 292 5821: 367-369. DOI: 10.1038/292367a0
[2] MAJERUS P W. Inositol phosphate biochemistry.[J]. Annual review of biochemistry, 1992, 61: 225-250. DOI: 10.1146/annurev.bi.61.070192.001301 |
| | Dopi-4,5-P2 (Na+ salt) Preparation Products And Raw materials |
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