DIPHTHERIA TOXIN
| 中文名称 | DIPHTHERIA TOXIN |
|---|---|
| 中文同义词 | 白喉毒素 来源于白喉杆菌;白喉毒素抗体;白喉毒素LR单克隆抗体;白喉毒素无毒突变蛋白CRM197 |
| 英文名称 | DIPHTHERIA TOXIN |
| 英文同义词 | DIPHTHERIA TOXIN;DIPHTHERIA TOXIN, CRM MUTANT;DIPHTHERIA TOXIN, UNNICKED, CORYNEBACTERIUM DIPHTHERIAE;CORYNEBACTERIUM DIPHTHERIAE TOXIN;(glu52)-diphtheria toxin from*corynebacterium dip;(GLU-52)-DIPHTHERIA TOXIN FROM*CORYNEBAC;[glu52]-diphtheria toxin from corynebacterium diphtheriae;Diphtheria toxin[Glu-52], Corynebacterium diphtheriae |
| CAS号 | 92092-36-9 |
| 分子式 | |
| 分子量 | 0 |
| EINECS号 | |
| 相关类别 | Cell Signaling and Neuroscience;Gene Regulation and Expression;BacteriaCell Signaling and Neuroscience;RNA-Protein Translation Inhibitors;Toxins and Venoms |
| Mol文件 | Mol File |
| 结构式 |
DIPHTHERIA TOXIN 性质
| 储存条件 | 2-8°C |
|---|---|
| 溶解度 | Water: soluble |
| 形态 | 冻干粉 |
Diphtheria toxin CRM197 是白喉毒素的一个无毒变种，具有一个单一的突变 (52 位的甘氨酸到谷氨酸的替代)，可以消除其毒性。CRM197 作为载体蛋白广泛应用于疫苗中。
Diphtheria toxin CRM197 is an enzymatically inactive and nontoxic form of diphtheria toxin that contains a single amino acid substitution (G52E). Being naturally nontoxic, CRM197 is an ideal carrier protein for conjugate vaccines against encapsulated bacteria and is currently used to vaccinate children globally against Haemophilus influenzae, pneumococcus, and meningococcus.
Diphtheria toxin, a single polypeptide secreted by lysogenic strains of
Corynebacterium diphtheria
, causes the disease diphtheria in humans by gaining entry into the cytoplasm of cells and inhibiting protein synthesis.
安全信息
| 危险品标志 | T+ |
|---|---|
| 危险类别码 | 28 |
| 安全说明 | 22-24/25-45-36/37-28 |
| 危险品运输编号 | 3172 |
| WGK Germany | 3 |
| RTECS号 | XW5807200 |
| 危险等级 | 6.1(a) |
| 包装类别 | I |
| 存储类别 | 11 - 可燃固体 |
| 提供商 | 语言 |
|---|---|
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英文
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