GALNON manufacturers
- GALNON
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- $817.00
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2026-05-11
- CAS:475115-35-6
- Purity:
- Supply Ability: 10g
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| Product Name: | GALNON | | Synonyms: | FMOC-BETA-CYCLOHEXYL-ALA-LYS-AMC;GALNON;3-CYCLOHEXYL-N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-ALANYL-N-(4-METHYL-2-OXO-2H-1-BENZOPYRAN-7-YL)-L-LYSINAMIDE;FMoc-b-cyclohexyl-Ala-Lys-AMC;FMoc-Cha-Lys-AMC;Galnon, Fmoc-Cha-Lys-AMC;L-Lysinamide, 3-cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- | | CAS: | 475115-35-6 | | MF: | C40H46N4O6 | | MW: | 678.82 | | EINECS: | | | Product Categories: | | | Mol File: | 475115-35-6.mol |  |
| | GALNON Chemical Properties |
| Boiling point | 937.5±65.0 °C(Predicted) | | density | 1.242±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | H2O: insoluble | | form | solid | | pka | 10.68±0.46(Predicted) | | color | white |
| | GALNON Usage And Synthesis |
| Uses | Galnon is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon exhibits anticonvulsant and anxiolytic effects[1][2]. | | Biological Activity | Novel non-peptide galanin GAL 1 receptor agonist (K i = 4.8 μ M). Stimulates insulin release in isolated pancreatic islets from normal and diabetic rats. Systemically active in vivo ; displays anticonvulsant activity following i.p. administration in mice. Central and peripheral administration also transiently inhibits food intake in rats and mice. | | References | [1] Bartfai T, et, al. Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10470-5. DOI:10.1073/pnas.0403802101
[2] Rajarao SJR, et, al. Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon. Neuropeptides. 2007 Oct;41(5):307-20. DOI:10.1016/j.npep.2007.05.001 |
| | GALNON Preparation Products And Raw materials |
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