- Quazinone
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- $495.00
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2026-07-14
- CAS:70018-51-8
- Purity:
- Supply Ability: 10g
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| | QUAZINONE Basic information |
| Product Name: | QUAZINONE | | Synonyms: | QUAZINONE;R 13-6438;RO 13-6438;(3R)-6-Chloro-1,5-dihydro-3-methylimidazo[2,1-b]quinazolin-2(3H)-one;Posicor;Imidazo(2,1-B)quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-methyl-, (R)-;Quazinona;Quazinona [spanish] | | CAS: | 70018-51-8 | | MF: | C11H10ClN3O | | MW: | 235.67 | | EINECS: | | | Product Categories: | | | Mol File: | 70018-51-8.mol |  |
| | QUAZINONE Chemical Properties |
| storage temp. | RT | | solubility | ethanol: soluble1mg/mL | | form | White to off-white solid. | | color | white | | Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months |
| | QUAZINONE Usage And Synthesis |
| Description | Ro 13-6438 (70018-51-8) is a selective inhibitor of phosphodiesterase III (PDE III, IC50 = 0.6 μM). | | Uses | Cardiotonic. | | Uses | Quazinone (Ro 13-6438) is a phosphodiesterase inhibitor and novel cardiotonic agent with vasodilating properties. | | References | [1] R EIGENMANN M H M Gerold. Cardiovascular profile of Ro 13-6438, a novel positive inotropic agent with vasodilating properties.[J]. Journal of Cardiovascular Pharmacology, 1984, 6 3: 511-519. DOI:10.1097/00005344-198405000-00021
[2] M HOLCK. Studies on the mechanism of positive inotropic activity of Ro 13-6438, a structurally novel cardiotonic agent with vasodilating properties.[J]. Journal of Cardiovascular Pharmacology, 1984, 6 3: 520-530. DOI:10.1097/00005344-198405000-00022 |
| | QUAZINONE Preparation Products And Raw materials |
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