| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
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MYF-01-37 manufacturers
- MYF-01-37
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- $55.00
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2026-07-27
- CAS:2416417-65-5
- Purity: 99.50%
- Supply Ability: 10g
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| | MYF-01-37 Basic information |
| Product Name: | MYF-01-37 | | Synonyms: | MYF-01-37;1-[3-Methyl-3-[3-(trifluoromethyl)anilino]pyrrolidin-1-yl]prop-2-en-1-one;Cys380,MYF 01 37,inhibit,Inhibitor,MYF0137,YAP/TEAD,Yes-associated protein,HEK293T,YAP;2-Propen-1-one, 1-[3-methyl-3-[[3-(trifluoromethyl)phenyl]amino]-1-pyrrolidinyl]-;1-(3-Methyl-3-((3-(trifluoromethyl)phenyl)amino)pyrrolidin-1-yl)prop-2-en-1-one;MYF-01-37, 10 mM in DMSO;MYF-01-37 ，S8950 | | CAS: | 2416417-65-5 | | MF: | C15H17F3N2O | | MW: | 298.3 | | EINECS: | | | Product Categories: | | | Mol File: | 2416417-65-5.mol |  |
| | MYF-01-37 Chemical Properties |
| Boiling point | 421.7±45.0 °C(Predicted) | | density | 1.245±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 250 mg/mL (838.08 mM; Need ultrasonic) | | pka | 5.17±0.20(Predicted) | | form | Solid | | color | White to off-white |
| | MYF-01-37 Usage And Synthesis |
| Uses | MYF-01-37 is a covalent TEAD inhibitor targeting Cys380. MYF-01-37 has a reversible inhibition on YAP/TEAD interaction[1]. | | IC 50 | YAP/TAZ-TEAD | | References | [1] Kari J Kurppa, et al. Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway. Cancer Cell. 2020 Jan 13;37(1):104-122.e12. DOI:10.1016/j.ccell.2019.12.006 |
| | MYF-01-37 Preparation Products And Raw materials |
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