| Company Name: |
BOC Sciences
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1-631-485-4226; 16314854226 |
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info@bocsci.com |
| Products Intro: |
Product Name:NV03 CAS:2448341-58-8 Purity:95% Remarks:Reach out to us for more information about custom solutions.
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Thieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazine-7(8H)-acetamide, N-[3-(diethylamino)propyl]-5,9-dimethyl-8-oxo- manufacturers
- NV03
-
- $1360.00
-
2026-07-16
- CAS:2448341-58-8
- Purity: 99.88%
- Supply Ability: 10g
- NV03
-
- $1360.00
-
2026-07-16
- CAS:2448341-58-8
- Purity: 99.88%
- Supply Ability: 10g
- NV03
-
- $2150.00
-
2025-09-03
- CAS:2448341-58-8
- Purity:
- Supply Ability: 10g
|
| | Thieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazine-7(8H)-acetamide, N-[3-(diethylamino)propyl]-5,9-dimethyl-8-oxo- Basic information |
| Product Name: | Thieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazine-7(8H)-acetamide, N-[3-(diethylamino)propyl]-5,9-dimethyl-8-oxo- | | Synonyms: | Thieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazine-7(8H)-acetamide, N-[3-(diethylamino)propyl]-5,9-dimethyl-8-oxo- | | CAS: | 2448341-58-8 | | MF: | C19H27N5O2S | | MW: | 389.52 | | EINECS: | | | Product Categories: | | | Mol File: | 2448341-58-8.mol | ![Thieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazine-7(8H)-acetamide, N-[3-(diethylamino)propyl]-5,9-dimethyl-8-oxo- Structure](CAS/20210111/GIF/2448341-58-8.gif) |
| | Thieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazine-7(8H)-acetamide, N-[3-(diethylamino)propyl]-5,9-dimethyl-8-oxo- Chemical Properties |
| density | 1.29±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 15.00±0.46(Predicted) | | form | Solid | | color | White to off-white |
| | Thieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazine-7(8H)-acetamide, N-[3-(diethylamino)propyl]-5,9-dimethyl-8-oxo- Usage And Synthesis |
| Uses | NV03 is a potent and selective antagonist of UHRF1 (Ubiquitin-like with PHD and RING finger domains 1)- H3K9me3 interaction by binding to UHRF1 tandem tudor domain, with a Kd of 2.4 μM. NV03 has anticancer activity[1]. | | IC 50 | UHRF1 | | References | [1] Senisterra G, et al. Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain. SLAS Discov. 2018 Oct;23(9):930-940. DOI:10.1177/2472555218766278 |
| | Thieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazine-7(8H)-acetamide, N-[3-(diethylamino)propyl]-5,9-dimethyl-8-oxo- Preparation Products And Raw materials |
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