Acetic acid, 2-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester

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Acetic acid, 2-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester Basic information
Product Name:Acetic acid, 2-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
Synonyms:Acetic acid, 2-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester;2,5-dioxopyrrolidin-1-yl 2-{2-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy}acetate;MAL-PEG2-SPA;Mal-PEG2-AA-NHS
CAS:329364-72-9
MF:C14H16N2O8
MW:340.29
EINECS:
Product Categories:
Mol File:329364-72-9.mol
Acetic acid, 2-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester Structure
Acetic acid, 2-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester Chemical Properties
Boiling point 507.5±60.0 °C(Predicted)
density 1.46±0.1 g/cm3(Predicted)
storage temp. -20°C, stored under nitrogen
pka-2.34±0.20(Predicted)
form Viscous Liquid
color Colorless to light yellow
InChIInChI=1S/C14H16N2O8/c17-10-1-2-11(18)15(10)5-6-22-7-8-23-9-14(21)24-16-12(19)3-4-13(16)20/h1-2H,3-9H2
InChIKeyHLLLISBRYDGYSK-UHFFFAOYSA-N
SMILESC(ON1C(=O)CCC1=O)(=O)COCCOCCN1C(=O)C=CC1=O
Safety Information
MSDS Information
Acetic acid, 2-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester Usage And Synthesis
UsesMal-PEG2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Acetic acid, 2-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester Preparation Products And Raw materials
Tag:Acetic acid, 2-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester(329364-72-9) Related Product Information
Mal-PEG6-NHS ester Mal-PEG4-NHS ester Mal-PEG3-NHS ester Mal-PEG8-NHS ester Mal-PEG5-NHS ester 2,5-dioxopyrrolidm-1 -yl 1 -(2,5-dioxo2,5-dihydro-1 H-pyrrol-1 -yl)-3,6.9,12.15t18,21,24.27,30,33,36-dodecaoxanonatnacontan-39-oate