- Mal-PEG6-NHS ester
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2025-06-07
- CAS:1599472-25-9
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | Mal-PEG6-NHS ester Basic information |
| Product Name: | Mal-PEG6-NHS ester | | Synonyms: | 2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oate;Mal-PEG6-NHS ester;4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,5-dioxo-1-pyrrolidinyl ester;Mal-PEG6-CH2CH2COONHS;Mal-PEG6-NHS ester ，S0630 | | CAS: | 1599472-25-9 | | MF: | C23H34N2O12 | | MW: | 530.52 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1599472-25-9.mol |  |
| | Mal-PEG6-NHS ester Chemical Properties |
| Boiling point | 635.8±65.0 °C(Predicted) | | density | 1.32±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Soluble in DCM | | pka | -2.34±0.20(Predicted) | | form | Liquid | | color | Colorless to light yellow | | InChI | InChI=1S/C23H34N2O12/c26-19-1-2-20(27)24(19)6-8-32-10-12-34-14-16-36-18-17-35-15-13-33-11-9-31-7-5-23(30)37-25-21(28)3-4-22(25)29/h1-2H,3-18H2 | | InChIKey | UUNUCVXNAHYFJP-UHFFFAOYSA-N | | SMILES | C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O |
| | Mal-PEG6-NHS ester Usage And Synthesis |
| Description | Mal-PEG6-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. | | Uses | Mal-PEG6-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 6-unit PEG and a NHS ester. | | IC 50 | Non-cleavable Linker | | References | [1] Kennett Sproge , et al. Relaxin prodrugs. WO2015067791A1. |
| | Mal-PEG6-NHS ester Preparation Products And Raw materials |
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