Propanamide, N-[(1S)-3-amino-1-cyano-3-oxopropyl]-2,2-dimethyl-3-[[4-(1-methyl-1H-indazol-5-yl)phenyl]sulfonyl]-

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Propanamide, N-[(1S)-3-amino-1-cyano-3-oxopropyl]-2,2-dimethyl-3-[[4-(1-methyl-1H-indazol-5-yl)phenyl]sulfonyl]- Suppliers list
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Email: marketing@targetmol.com

Propanamide, N-[(1S)-3-amino-1-cyano-3-oxopropyl]-2,2-dimethyl-3-[[4-(1-methyl-1H-indazol-5-yl)phenyl]sulfonyl]- manufacturers
Propanamide, N-[(1S)-3-amino-1-cyano-3-oxopropyl]-2,2-dimethyl-3-[[4-(1-methyl-1H-indazol-5-yl)phenyl]sulfonyl]- Basic information
Product Name:Propanamide, N-[(1S)-3-amino-1-cyano-3-oxopropyl]-2,2-dimethyl-3-[[4-(1-methyl-1H-indazol-5-yl)phenyl]sulfonyl]-
Synonyms:Propanamide, N-[(1S)-3-amino-1-cyano-3-oxopropyl]-2,2-dimethyl-3-[[4-(1-methyl-1H-indazol-5-yl)phenyl]sulfonyl]-;Legumain inhibitor 1
CAS:2361157-34-6
MF:C23H25N5O4S
MW:467.54
EINECS:
Product Categories:
Mol File:2361157-34-6.mol
Propanamide, N-[(1S)-3-amino-1-cyano-3-oxopropyl]-2,2-dimethyl-3-[[4-(1-methyl-1H-indazol-5-yl)phenyl]sulfonyl]- Structure
Propanamide, N-[(1S)-3-amino-1-cyano-3-oxopropyl]-2,2-dimethyl-3-[[4-(1-methyl-1H-indazol-5-yl)phenyl]sulfonyl]- Chemical Properties
Boiling point 836.4±65.0 °C(Predicted)
density 1.34±0.1 g/cm3(Predicted)
pka12.29±0.46(Predicted)
form Solid
color White to yellow
Safety Information
MSDS Information
Propanamide, N-[(1S)-3-amino-1-cyano-3-oxopropyl]-2,2-dimethyl-3-[[4-(1-methyl-1H-indazol-5-yl)phenyl]sulfonyl]- Usage And Synthesis
UsesLegumain inhibitor 1 is a potent and selective Legumain inhibitor with an IC50 of 3.6 nM. Legumain inhibitor 1 can be used for cancer research[1].
References[1] Sharon L Eddie, et al. Identification and SAR exploration of a novel series of Legumain inhibitors. Bioorg Med Chem Lett. 2019 Jun 15;29(12):1546-1548. DOI:10.1016/j.bmcl.2019.03.019
Propanamide, N-[(1S)-3-amino-1-cyano-3-oxopropyl]-2,2-dimethyl-3-[[4-(1-methyl-1H-indazol-5-yl)phenyl]sulfonyl]- Preparation Products And Raw materials
Tag:Propanamide, N-[(1S)-3-amino-1-cyano-3-oxopropyl]-2,2-dimethyl-3-[[4-(1-methyl-1H-indazol-5-yl)phenyl]sulfonyl]-(2361157-34-6) Related Product Information
Propanamide, N-[(1S)-3-amino-1-cyano-3-oxopropyl]-2,2-dimethyl-3-[[4-(1-methyl-1H-indazol-5-yl)phenyl]sulfonyl]- Anti-cancer compound library L-Prolinamide, N-[6-[2-[5-(1-ethyl-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene)-1,3-pentadien-1-yl]-3,3-dimethyl-5-sulfo-3H-indolio]-1-oxohexyl]-L-α-glutamyl-N-[(1S)-3-[[4-[[[3-[[[1-[[2-[3,6-bis(2,3-dihydro-1H-indol-1-yl)xanthylium-9-yl]phenyl]sulfonyl]-4-piperidinyl]carbonyl]amino]propyl]amino]carbonyl]-2,6-dimethylbenzoyl]oxy]-1-(carboxymethyl)-2-oxopropyl]- β-Alaninamide, 1-[[(3′-ethoxy[1,1′-biphenyl]-4-yl)methoxy]carbonyl]-L-prolyl-3-cyano-, (3S)- L-Alanine, N-[(phenylmethoxy)carbonyl]-L-alanyl-, 2-(2-amino-2-oxoethyl)-2-[(2E)-4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,4-dioxo-2-buten-1-yl]hydrazide