2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one

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2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Suppliers list
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2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Basic information
Product Name:2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
Synonyms:2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one;4-[4-[4-(4-Methoxyphenyl)piperazino]phenyl]-3,4-dihydro-2H-1,2,4-triazole-3-one;Posaconazole inter-5;4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-1H-1,2,4-triazol-5-one;2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)PIPERAZIN-1-YL]PHENYL]-3H-1,2,4-TRIAZOL-3-ONE(WXC08779);4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5-one;3H-1,2,4-Triazol-3-one,2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-;4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one
CAS:74853-07-9
MF:C19H21N5O2
MW:351.4
EINECS:278-009-6
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:74853-07-9.mol
2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Structure
2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Chemical Properties
Melting point 270-277°C (dec.)
density 1.30±0.1 g/cm3(Predicted)
vapor pressure 0-0Pa at 20-25℃
storage temp. Sealed in dry,2-8°C
solubility DMSO (Slightly, Heated)
form Solid:particulate/powder
pka10.16±0.20(Predicted)
LogP2.3 at pH7
Safety Information
MSDS Information
2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Usage And Synthesis
Chemical PropertiesOff-White Solid
Uses4-{[4-(4-Methyloxyphenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one, is an intermediate for the synthesis of Itraconazole (I937500), an Antifungal.
2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Preparation Products And Raw materials
Preparation Products2,4-Dihydro-4-[(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazole-3-one-->2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-
Tag:2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one(74853-07-9) Related Product Information
Posaconazole Diastereoisomer 12 Posaconazole-d4 Posaconazole DiastereoisoMer interMediate 2 Posaconazole-d5 Posaconazole 1H-1,2,4-Triazole, 1-[[(2S)-2-(2,4-difluorophenyl)oxiranyl]methyl]- Hydroxy itraconazole 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one Itraconazole 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one SAPERCONAZOLE KETO ITRACONAZOLE 3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-, (S)- 2-sec-Butyl-d5-4-(4-[4-(4-methyloxy-phenyl)-piperazin-1-yl]-phenyl)-2,4-dihydro-[1,2,4]-triazol-3-one Itraconazole-5-methyl-2-isopentane 3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-, (R)- Benzyl hydroxy itraconazole MITRATAPID