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| | SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain (human IgG1 Fc-tagged) Basic information |
| | SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain (human IgG1 Fc-tagged) Chemical Properties |
| | SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain (human IgG1 Fc-tagged) Usage And Synthesis |
| Description | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped positive-stranded RNA virus, a member of the Betacoronavirus genus, and the causative agent of COVID-19.1,2,3,4,5 The SARS-CoV-2 spike glycoprotein, also known as the surface glycoprotein, is located on the outer envelope of the virion.1 It is composed of an S1 and S2 subunit divided by a furin S-cleavage site not found in other SARS-CoVs.6,7 The S1 subunit contains the receptor-binding domain (RBD), which binds to the carboxypeptidase angiotensin-converting enzyme 2 (ACE2), and the S1 and S2 subunits are cleaved by the protease TMPRSS2 to facilitate viral fusion with the host cell membrane.8,9,10 In this way, ACE2 acts as the functional receptor for SARS-CoV-2. Cayman’s SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain (human IgG1 Fc-tagged) protein can be used as an antigen or for Western blot, ELISA, protein-protein interaction studies, and other in vitro binding and in vivo functional assays.WARNING This product is not for human or veterinary use. |
| | SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain (human IgG1 Fc-tagged) Preparation Products And Raw materials |
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