| Company Name: |
BOC Sciences |
| Tel: |
16314854226; +8616314854226 |
| Email: |
inquiry@bocsci.com |
CFM1571hydrochloride manufacturers
|
| | CFM1571hydrochloride Basic information |
| Product Name: | CFM1571hydrochloride | | Synonyms: | CFM1571hydrochloride;3-[3-(Dimethylamino)propoxy]-N-(4-methoxyphenyl)-1-(phenylmethyl)-1H-pyrazole-5-carboxamidehydrochloride;CFM 1571;1H-Pyrazole-5-carboxamide, 3-[3-(dimethylamino)propoxy]-N-(4-methoxyphenyl)-1-(phenylmethyl)-;CFM-1571(free base);1-Benzyl-3-(3-dimethylaminopropyloxy)-5-(4-methoxyphenylaminocarbonyl)-1H-pyrazole | | CAS: | 268725-86-6 | | MF: | C23H28N4O3 | | MW: | 408.49 | | EINECS: | | | Product Categories: | | | Mol File: | 268725-86-6.mol |  |
| | CFM1571hydrochloride Chemical Properties |
| Melting point | >182° C (dec.) | | storage temp. | Store at +4°C | | solubility | DMSO (Slghtly), Methanol (Slightly) | | form | Solid | | color | White to Off-White |
| | CFM1571hydrochloride Usage And Synthesis |
| Uses | CFM 1571 is the free base of CFM 1571 Hydrochloride (C291720), which acts as a soluble guanylyl cyclase (sGC) activator while ignoring adenylyl cyclase. Inhibits collagen-stimulated platelet aggregation in vitro. | | Definition | ChEBI: 5-[3-(dimethylamino)propoxy]-N-(4-methoxyphenyl)-2-(phenylmethyl)-3-pyrazolecarboxamide is an aromatic amide. | | Biological Activity | Soluble guanylyl cyclase (sGC) activator (EC 50 = 5.49 μ M). Does not activate adenylyl cyclase, shows no significant inhibition of phosphodiesterases and displays minimal inhibition of iNOS (25%) and nNOS (17%). Inhibits collagen-stimulated platelet aggregation in vitro (IC 50 = 2.84 μ M). |
| | CFM1571hydrochloride Preparation Products And Raw materials |
|