| Company Name: |
Merck KGaA |
| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
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| | 2',7-Dihydroxy-4'-methoxyisoflavan Basic information |
| Product Name: | 2',7-Dihydroxy-4'-methoxyisoflavan | | Synonyms: | [S,(+)]-3,4-Dihydro-3-(2-hydroxy-4-methoxyphenyl)-2H-1-benzopyran-7-ol;2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(2-hydroxy-4-methoxyphenyl)-, (3S)-;(+)-Vestitol | | CAS: | 20879-05-4 | | MF: | C16H16O4 | | MW: | 272.3 | | EINECS: | | | Product Categories: | | | Mol File: | 20879-05-4.mol |  |
| | 2',7-Dihydroxy-4'-methoxyisoflavan Chemical Properties |
| Melting point | 156 °C | | Boiling point | 418.5±45.0 °C(Predicted) | | density | 1.282±0.06 g/cm3(Predicted) | | storage temp. | -10 to -25°C | | solubility | DMSO: 2mg/mL, clear | | pka | 9.53±0.40(Predicted) | | form | powder | | color | white to beige |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | 2',7-Dihydroxy-4'-methoxyisoflavan Usage And Synthesis |
| Definition | ChEBI: The S-enantiomer of vestitol. | | Biological Activity | Hydroxyisoflavan isolated from Cuban and Brazilian red propolis th at exhibits potent anti-inflammatory, anti-viral, and antiparasitic activities.
(+)-Vestitol is a hydroxyisoflavan isolated from Cuban and Brazilian red propolis, licorice root and other sources th at exhibits potent anti-inflammatory, anti-viral, and antiparasitic activities. Apparently Vestitol inhibits release of the chemokines CXCL1/KC and CXCL2/MIP-2 from macrophages. Vestitol strongly inhibits Chikungunya virus infection. Vestitol exhibits anti-trypanosomal activity against T. brucei and T. congolense (EC50 3.86 and 4.36 μg/ml). |
| | 2',7-Dihydroxy-4'-methoxyisoflavan Preparation Products And Raw materials |
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