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| | Jatrophone Basic information |
| Product Name: | Jatrophone | | Synonyms: | Jatrophone;(2R,3aR,9E,12Z)-2,3,7,8-Tetrahydro-2,5,8,8,12-pentamethyl-3a,6-epoxy-3aH-cyclopentacyclododecene-4,11-dione;3a,6-Epoxy-3aH-cyclopentacyclododecene-4,11-dione, 2,3,7,8-tetrahydro-2,5,8,8,12-pentamethyl-, (2R,3aR,9E,12Z)-;Jatropha principle;NSC 135037;NSC135037;NSC-135037 | | CAS: | 29444-03-9 | | MF: | C20H24O3 | | MW: | 312.4 | | EINECS: | | | Product Categories: | | | Mol File: | 29444-03-9.mol |  |
| | Jatrophone Chemical Properties |
| | Jatrophone Usage And Synthesis |
| Uses | Jatrophone is a diterpenoid with anticancer activity isolated from Jatropha isabelli. Jatrophone interferes with the Wnt/β-catenin pathway to inhibit the proliferation and epithelial-mesenchymal transition (EMT) of triple-negative breast cancer cells. | | Definition | A diterpenoid growth inhibitor isolated from an alcohol extract of the plant Jatropha gossypiifolia. Its unique structure includes a 12membered ring. It is readily attacked by nucleophiles. Useful in study of tumor growth inhibition and other biochemical research. | | References | [1] The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer |
| | Jatrophone Preparation Products And Raw materials |
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