5,8-Dideazapteroylornithine

5,8-Dideazapteroylornithine Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

5,8-Dideazapteroylornithine manufacturers

  • DDPO
  • DDPO pictures
  • $1980.00
  • 2026-05-11
  • CAS:118675-83-5
  • Purity:
  • Supply Ability: 10g
5,8-Dideazapteroylornithine Basic information
Product Name:5,8-Dideazapteroylornithine
Synonyms:5,8-Dideazapteroylornithine;L-Ornithine, N2-[4-[[(2-amino-1,4-dihydro-4-oxo-6-quinazolinyl)methyl]amino]benzoyl]- (9CI);8-Dideazapteroylornithine;DDPO
CAS:118675-83-5
MF:C21H24N6O4
MW:424.45
EINECS:
Product Categories:
Mol File:118675-83-5.mol
5,8-Dideazapteroylornithine Structure
5,8-Dideazapteroylornithine Chemical Properties
Safety Information
MSDS Information
5,8-Dideazapteroylornithine Usage And Synthesis
DescriptionDDPO is a folypolyglutamate synthetase antagonist.
UsesDDPO is an inhibitor for dihydrofolate reductase (DHFR) with an IC50 of 0.035 μM. DDPO inhibits the cell growth of cancer cell L1210 and WI-L2with IC50 of 5 and 0.28 μM[1].
References[1] Rosowsky A, et al., Synthesis and in vitro biological activity of new deaza analogues of folic acid, aminopterin, and methotrexate with an L-ornithine side chain.
5,8-Dideazapteroylornithine Preparation Products And Raw materials
Tag:5,8-Dideazapteroylornithine(118675-83-5) Related Product Information
CB 3705 10-formyldihydrofolate 4-[N-(2,4-Diamino-6-pteridinylmethyl)-N-methylamino] benzoic acid Piritrexim 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine, 7-[(2-fluoro-4-pyridinyl)methyl]- DAMPA Methyl Ester