| Company Name: |
BioBioPha Co., Ltd.
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| Tel: |
0871-65217109 13211707573; |
| Email: |
y.liu@mail.biobiopha.com |
| Products Intro: |
Product Name:Neritaloside CAS:465-13-4 Purity:97.5% Package:5mg Remarks:BBP01917
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| | neritaloside Basic information |
| Product Name: | neritaloside | | Synonyms: | neritaloside;Card-20(22)-enolide, 16-(acetyloxy)-3-[(6-deoxy-3-O-methyl-β-D-galactopyranosyl)oxy]-14-hydroxy-, (3β,5β,16β)- | | CAS: | 465-13-4 | | MF: | C32H48O10 | | MW: | 592.73 | | EINECS: | | | Product Categories: | | | Mol File: | 465-13-4.mol |  |
| | neritaloside Chemical Properties |
| Melting point | 135-140 °C | | Boiling point | 729.4±60.0 °C(Predicted) | | density | 1.30±0.1 g/cm3(Predicted) | | pka | 12.92±0.70(Predicted) |
| | neritaloside Usage And Synthesis |
| Uses | Neritaloside could be isolated from nerium oleander. Neritaloside has central nervous system (CNS) depressant effect[1][2. | | in vivo | Neritaloside (25 mg/kg; i.p.; for 6 hours; mice of NMRI strain) exhibits central nervous system depressant activity in mice at a dose of 25 mg/kg[2. | Animal Model: | Mice of NMRI strain (18-22 g) [2 | | Dosage: | 25 mg/kg | | Administration: | Intraperitoneal injection; for 6 hours | | Result: | Showed sedation in mice at 25 mg/kg dose. |
| | References | [1] Rashan LJ, et, al. Characterization of the anticancer properties of monoglycosidic cardenolides isolated from Nerium oleander and Streptocaulon tomentosum. J Ethnopharmacol. 2011 Apr 12;134(3):781-8. DOI:10.1016/j.jep.2011.01.038 [2] Begum S, et, al. Bio-active cardenolides from the leaves of Nerium oleander. Phytochemistry. 1999 Feb;50(3):435-8. DOI:10.1016/s0031-9422(98)00523-8 |
| | neritaloside Preparation Products And Raw materials |
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