HSD17B13-IN-7

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HSD17B13-IN-7 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
HSD17B13-IN-7 Basic information
Product Name:HSD17B13-IN-7
Synonyms:HSD17B13-IN-7;Benzamide, 3-fluoro-4-hydroxy-N-[[trans-1-hydroxy-4-(phenoxymethyl)cyclohexyl]methyl]-
CAS:863564-16-3
MF:C21H24FNO4
MW:373.42
EINECS:
Product Categories:
Mol File:863564-16-3.mol
HSD17B13-IN-7 Structure
HSD17B13-IN-7 Chemical Properties
Boiling point 551.4±40.0 °C(predicted)
density 1.245±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka7.30±0.20(predicted)
Safety Information
MSDS Information
HSD17B13-IN-7 Usage And Synthesis
UsesHSD17B13-IN-7 (compound 1), a fluorophenol-containing compound, is a potent HSD17B13 inhibitor with IC50s of 0.18 μM and 0.25 μM β-estradiol and Leukotriene B4 as substrates, respectively. HSD17B13-IN-7 is a potent N-methyl-D-aspartate (NMDA) NR2B receptor antagonist. HSD17B13-IN-7 has the potential for non-alcoholic fatty liver disease research[1].
IC 50NR2B
References[1] Shenping Liu, et al. Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13. Nat Commun. 2023 Aug 24;14(1):5158. DOI:10.1038/s41467-023-40766-0
HSD17B13-IN-7 Preparation Products And Raw materials
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