DQP-26 manufacturers
- DQP-26
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2026-05-11
- CAS:1449373-99-2
- Purity:
- Supply Ability: 10g
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| Product Name: | DQP-26 | | Synonyms: | DQP-26;1H-Pyrazole-1-butanoic acid, 5-(4-chlorophenyl)-3-[4-(4-chlorophenyl)-1,2-dihydro-2-oxo-3-quinolinyl]-4,5-dihydro-γ-oxo- | | CAS: | 1449373-99-2 | | MF: | C28H21Cl2N3O4 | | MW: | 534.39 | | EINECS: | | | Product Categories: | | | Mol File: | 1449373-99-2.mol |  |
| | DQP-26 Chemical Properties |
| density | 1.452±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 4.843±0.17(predicted) | | form | Solid | | color | White to off-white |
| | DQP-26 Usage And Synthesis |
| Uses | DQP-26 is a potent NMDAR negative allosteric modulator with IC50 values of 0.77 μM and 0.44 μM for GluN2C and GluN2D, respectively. DQP-26 has the potential for NMDAR-associated neurological disease research[1]. | | References | [1] Michael P D'Erasmo, et al. Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor. ACS Chem Neurosci. 2023 Sep 6;14(17):3059-3076. DOI:10.1021/acschemneuro.3c00181 |
| | DQP-26 Preparation Products And Raw materials |
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