| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Pyrithione cadmium
CAS:18897-36-4
Package:25mg/RMB 10600;100mg/RMB 17500;50mg/RMB 13800
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CADMIUMPYRIDINETHIONE manufacturers
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| | CADMIUMPYRIDINETHIONE Basic information |
| | CADMIUMPYRIDINETHIONE Chemical Properties |
| | CADMIUMPYRIDINETHIONE Usage And Synthesis |
| Uses | Cadmium pyrithione is a metal compound that inhibits protein deubiquitinase activity. Cadmium pyrithione treatment results in significant accumulation of ubiquitinated proteins in cancer cells and primary leukemia cells. Cadmium pyrithione strongly inhibits the activity of proteasome deubiquitinase (such as USP14 and UCHL5), but has a smaller inhibitory effect on 20S proteasome activity. The anticancer activity of Cadmium pyrithione is associated with the induction of apoptosis through caspase activation. Furthermore, Cadmium pyrithione inhibition inhibited proteasome function and suppressed tumor growth in animal xenograft models[1]. | | Safety Profile | Confirmed human
carcinogen. Poison by ingestion and
intravenous routes. When heated to
decomposition it emits toxic fumes of NO,,
SO,, and Cd. | | References | [1] Cadmium pyrithione suppresses tumor growth in vitro and in vivo through inhibition of proteasomal deubiquitinase |
| | CADMIUMPYRIDINETHIONE Preparation Products And Raw materials |
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