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| | 1-(1,2-Dihexadecanoylphosphatidyl)inositol-5-phosphate, ammonium salt Basic information |
| | 1-(1,2-Dihexadecanoylphosphatidyl)inositol-5-phosphate, ammonium salt Chemical Properties |
| solubility | CHCl3:CH3OH:H2O (3:2:0.5): > 1 mg/mlH2O: < 1 mg/ml |
| | 1-(1,2-Dihexadecanoylphosphatidyl)inositol-5-phosphate, ammonium salt Usage And Synthesis |
| Description | PtdIns-(5)-P1 can be further phosphorylated to give diphosphates such as PtdIns-(4,5)-P2. These can also be cleaved by PI-specific phospholipase C (PLC) to give inositol triphosphates (IP3). The diacyl glycerol and IP3 generated by this PLC-cleavage are also part of a complex biochemical and signal transduction cascade which has not been entirely elucidated. For some additional reading, please see references 1,2,3.WARNING This product is not for human or veterinary use. | | References | [1] MAJERUS P W. Inositol phosphate biochemistry.[J]. Annual review of biochemistry, 1992, 61: 225-250. DOI: 10.1146/annurev.bi.61.070192.001301 [2] L J PIKE L C. Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains.[J]. The Journal of Biological Chemistry, 1996, 271 43: 26453-26456. DOI: 10.1074/jbc.271.43.26453 [3] BERRIDGE M J. Inositol trisphosphate and calcium signalling[J]. Nature, 1993, 361 6410: 315-325. DOI: 10.1038/361315a0 |
| | 1-(1,2-Dihexadecanoylphosphatidyl)inositol-5-phosphate, ammonium salt Preparation Products And Raw materials |
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