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| | N-omega-Hydroxy-nor-L-arginine, diacetate salt Basic information |
| Product Name: | N-omega-Hydroxy-nor-L-arginine, diacetate salt | | Synonyms: | L-2-AMINO-(4-(2'-HYDROXYGUANIDINO)BUTYRIC ACID), 2CH3CO2H;N---Hydroxy-nor-L-arginine;(S,E)-2-aMino-4-(2-hydroxyguanidino)butanoic acid;L-2-AMino-4-(2'-hydroxyguanidino)-butyric acid, nor-NOHA, H-Nar(OH)-OH;N-o-Hydroxy-L-norarginine;L-2-Amino-{4-(2'-hydroxyguanidino)butyric acid diacetate;nor-NOHA diacetate;N-w-Hydroxy-L-norarginine diacetate salt≥ 97% (TLC) | | CAS: | 189302-40-7 | | MF: | C5H12N4O3 | | MW: | 176.17 | | EINECS: | | | Product Categories: | proteins | | Mol File: | 189302-40-7.mol |  |
| | N-omega-Hydroxy-nor-L-arginine, diacetate salt Chemical Properties |
| Boiling point | 391.515±52.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.634±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | Store at 0°C | | solubility | water: 50 mg/mL | | pka | 2.209±0.10(predicted) | | form | White to slightly yellowish powder. | | color | off-white | | Water Solubility | water: 50mg/mL | | InChIKey | PQFYTZJPYBMTCT-QTNFYWBSSA-N | | SMILES | N(O)\C(=N\CC[C@H](N)C(=O)O)\N.OC(=O)C.OC(=O)C |
| WGK Germany | WGK 1 | | Storage Class | 11 - Combustible Solids |
| | N-omega-Hydroxy-nor-L-arginine, diacetate salt Usage And Synthesis |
| Chemical Properties | Off-white powder | | Uses | A potent, selective, competitive, and high affinity inhibitor of arginase. Shown to inhibit arginase from rat liver (IC50 = 2 µM) and mouse macrophages (IC50 = 50 µM). Shown to specifically interact with the manganese-cluster of the enzyme active site. Does not function as a substrate or as an inhibitor for NOS. Hence, nor-NOHA may be a useful tool to study the interplays between arginase and NOS. | | Definition | ChEBI: Nomega-hydroxy-nor-l-arginine is a L-alpha-amino acid. | | General Description | A potent, selective, competitive, and high affinity inhibitor of arginase. Shown to inhibit arginase from rat liver (IC50 = 2 μM) and mouse macrophages (IC50 = 50 μM). Shown to specifically interact with the manganese-cluster of the enzyme active site. Does not function as a substrate or as an inhibitor for NOS. Hence, nor-NOHA may be a useful tool to study the interplays between arginase and NOS. | | Biochem/physiol Actions | Primary Targetarginase from rat liver |
| | N-omega-Hydroxy-nor-L-arginine, diacetate salt Preparation Products And Raw materials |
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