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| | 2-Aminomethyl-3-fluoropyridine dihydrochloride Basic information |
| Product Name: | 2-Aminomethyl-3-fluoropyridine dihydrochloride | | Synonyms: | 2-AMINOMETHYL-3-FLUOROPYRIDINE DIHYDROCHLORIDE;2-AMinoMethyl-3-fluoropyr...;2-AMinoMethyl-3-fluoropyridine hydrochloride;(3-Fluoropyridin-2-yl)MethanaMine dihydrochloride;3-Fluoro-2-pyridineMethanaMine 2HCl;C-(3-FLUOROPYRIDIN-2-YL)-METHAMINE HYDROCHLORIDE;2-(Aminomethyl)-3-fluoropyridine 2HCl;(3-fluoro-2-pyridyl)methanamine dihydrochloride | | CAS: | 312904-49-7 | | MF: | C6H8ClFN2 | | MW: | 162.59 | | EINECS: | | | Product Categories: | | | Mol File: | 312904-49-7.mol |  |
| | 2-Aminomethyl-3-fluoropyridine dihydrochloride Chemical Properties |
| storage temp. | Inert atmosphere,Room Temperature | | Appearance | Light yellow to light brown Solid | | InChI | InChI=1S/C6H7FN2.ClH/c7-5-2-1-3-9-6(5)4-8;/h1-3H,4,8H2;1H | | InChIKey | ATBRZELHPCIJTK-UHFFFAOYSA-N | | SMILES | C(C1N=CC=CC=1F)N.Cl |
| | 2-Aminomethyl-3-fluoropyridine dihydrochloride Usage And Synthesis |
| Uses | 2-Aminomethyl-3-fluoropyridine dihydrochloride is a key intermediate in the synthesis of thrombin inhibitors. | | References | [1] Papaioannou*, N., Fray*, M. J., Rennhack, A., Sanderson, T. J., & Stokes, J. E. (2020). Regioselective Amidomethylation of 4-Chloro-3-fluoropyridine by Metalation and Minisci-Type Reactions. <i>The Journal of Organic Chemistry</i>, <i>85 19</i>, 12067–12079. https://doi.org/10.1021/acs.joc.0c01168
[2] Ashwood, M. S., Alabaster, R. J., Cottrell, I. F., Cowden, C. J., Davies, A. J., Dolling, U. H., Emerson, K. M., Gibb, A. D., Hands, D., Wallace, D. J., & Wilson, R. D. (2004). Development of a Scaleable Synthesis of a 3-Aminopyrazinone Acetamide Thrombin Inhibitor. <i>Organic Process Research &amp; Development</i>, <i>8 2</i>, 192–200. https://doi.org/10.1021/op0341420
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| | 2-Aminomethyl-3-fluoropyridine dihydrochloride Preparation Products And Raw materials |
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