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| | ALYTESIN Basic information |
| Product Name: | ALYTESIN | | Synonyms: | PYR-GLY-ARG-LEU-GLY-THR-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2;ALYTESIN;Alytesin Pyr-Gly-Arg-Leu-Gly-Thr-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2;GLP-GLY-ARG-LEU-GLY-THR-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2;[Gly2, Thr6]-Bombesin;pGlu-Gly-Arg-Leu-Gly-Thr-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2;[Gly2, Thr6]-Bombesin, pGlu-Gly-Arg-Leu-Gly-Thr-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2;GLP-GLY-ARG-LEU-GLY-THR-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2: GLP-GRLGTQWAVGHLM-NH2 | | CAS: | 31078-12-3 | | MF: | C68H106N22O17S | | MW: | 1535.77 | | EINECS: | | | Product Categories: | Neuromedins and related;Peptide | | Mol File: | 31078-12-3.mol |  |
| | ALYTESIN Chemical Properties |
| density | 1.47±0.1 g/cm3(Predicted) | | RTECS | PC4360120 | | storage temp. | −20°C | | pka | 13.11±0.46(Predicted) | | form | Solid | | Water Solubility | Soluble to 1 mg/ml in water | | Sequence | {Glp}-Gly-Arg-Leu-Gly-Thr-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 |
| | ALYTESIN Usage And Synthesis |
| Uses | Alytesin, a bombesin-like peptide, is found in extracts of the skin of Alytes obstetricans. Alytesin reduces gastric acid secretion and induces hypertension. Alytesin also induces short-term anorexigenic effects in neonatal chicks[1][2][3] | | References | [1] Guglietta A, et al. Central neuromodulation of gastric acid secretion by bombesin-like peptides. Peptides. 1985;6 Suppl 3:75-81. DOI:10.1016/0196-9781(85)90354-7
[2] Erspamer V, et al. Some pharmacological actions of alytesin and bombesin. J Pharm Pharmacol. 1970 Nov;22(11):875-6. DOI:10.1111/j.2042-7158.1970.tb08465.x
[3] Cline MA, et al. Central and peripheral alytesin cause short-term anorexigenic effects in neonatal chicks. Neuropeptides. 2008 Jun;42(3):283-91. DOI:10.1016/j.npep.2008.02.004 |
| | ALYTESIN Preparation Products And Raw materials |
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