N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sphinganine

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N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sphinganine Basic information
Product Name:N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sphinganine
Synonyms:NBD-C12-SAFINGOL;N-ACYL-SPHINGANINE (C12 NBD);N-(NBD-AMINOLAUROYL)SAFINGOL;N-(NBD-AMINOLAUROYL)SPHINGANINE;N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-L-THREO-SPHINGANINE;N-[6-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-L-THREO-SPHINGANINE;C12 NBD dihydro Ceramide (d18:0/12:0);N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE;C12-NBD SPHINGANINE
CAS:474943-05-0
MF:C36H63N5O6
MW:661.92
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Mol File:Mol File
N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sphinganine Structure
N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sphinganine Chemical Properties
density 1.095±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml
form A solid
pka14.30±0.20(Predicted)
AppearanceSolid Powder
Safety Information
Hazard Codes Xn
Risk Statements 22-38-40-48/20/22
Safety Statements 36/37
RIDADR UN 1888 6.1/PG 3
WGK Germany 3
Storage Class11 - Combustible Solids
MSDS Information
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N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sphinganine Usage And Synthesis
Description

N-(NBD-Aminolauroyl)safingol is a fluorescent group C12 NBD-tagged probe for labeling membranous fatty acid phospholipids.

UsesC-12 NBD-dihydro-Ceramide is a fluorescent ceramidase substrate. C-12 NBD-dihydro-Ceramide compound is a fluorescent ceramide analog which contains a saturated bond in the C4-C5 position of the sphingosine backbone. It can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources. C-12 NBD-dihydro-ceramide may exhibit reduced activity in ceramidase assays compared to C-12 NBD ceramide. This is based on the observation that saturation of the C4-C5 sphingosine bond in C16-ceramide results in approximately a 10-fold reduction in efficiency as a substrate for rat brain ceramidase compared to the unsaturated substrate. Yet, experimental characterization of C-12 NBD-dihydro-ceramide as a ceramidase substrate needs to be performed.
N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sphinganine Preparation Products And Raw materials
Tag:N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sphinganine(474943-05-0) Related Product Information
C6 NBD L-threo dihydro Ceramide (d18:0/6:0) C6 NBD SAFINGOL C12 NBD L-threo dihydro Ceramide (d18:0/12:0) N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-ceramide C12 NBD L-threo Ceramide (d18:1/12:0) HATU