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| | Caffeic acid-pyeeie Basic information |
| Product Name: | Caffeic acid-pyeeie | | Synonyms: | N-[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]-O-phosphono-L-tyrosyl-L-a-glutamyl-L-a-glutamyl-L-isoleucyl-L-glutamicacid;N-[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]-O-phosphono-L-tyrosyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-glutamicacid;N-[3-(3,4-DIHYDROXYPHENYL)-1-OXO-2-PROPENYL]-O-PHOSPHONO-L-TYROSYL-L-ALPHA-GLUTAMYL-L-ALPHA-GLUTAMYL-L-ISOLEUCYL-L-GLUTAMIC ACID;L-Glutamic acid, N-[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]-O-phosphono-L-tyrosyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl- (9CI);Caffeic acid-pyeeie | | CAS: | 507471-72-9 | | MF: | C39H50N5O19P | | MW: | 923.81 | | EINECS: | | | Product Categories: | | | Mol File: | 507471-72-9.mol |  |
| | Caffeic acid-pyeeie Chemical Properties |
| density | 1.487±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 1.269±0.30(predicted) |
| | Caffeic acid-pyeeie Usage And Synthesis |
| Uses | Caffeic acid-pYEEIE, a non-phosphopeptide inhibitor, exhibits potent binding affinity for the GST-Lck-SH2 domain[1]. | | Biological Activity | Phosphopeptide ligand for the src SH2 domain (IC 50 = 42 nM); displays 30-fold higher affinity than N-acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu (Ac-pYEEIE, N-Acetyl-O-phosphono-L-tyrosyl-L-a-glutamyl-L-a-glutamyl]-L-a-glutamyl-L-isoleucyl]-L-glutamic acid). | | storage | Store at -20°C | | References | [1] See-Hyoung Park, et al. Design and characterization of non-phosphopeptide inhibitors for Src family SH2 domains. Bioorg Med Chem Lett. 2002 Oct 7;12(19):2711-4. DOI:10.1016/s0960-894x(02)00523-1 |
| | Caffeic acid-pyeeie Preparation Products And Raw materials |
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