|
|
| | 3-Chloro-2-hydrazino-1,2-dihydropyrazine hydrochloride Basic information |
| Product Name: | 3-Chloro-2-hydrazino-1,2-dihydropyrazine hydrochloride | | Synonyms: | 2-CHLORO-3-HYDRAZINYLPYRAZINE;3-Chloro-2(H)-pyrazinone hydrazone;(3-Chloropyrazin-2-yl)hydrazine;2-Chloro-3-hydrazinopyrazine;2-chloro-3-hydrazinopyrazine(SALTDATA: FREE);2-(3-chloropyrazin-2-yl)hydrazine;Pyrazine,2-chloro-3-hydrazinyl-;(3-Chloro-pyrazin-2-yl)-hydrazine hydrochloride | | CAS: | 63286-28-2 | | MF: | C4H5ClN4 | | MW: | 144.56 | | EINECS: | | | Product Categories: | | | Mol File: | 63286-28-2.mol |  |
| | 3-Chloro-2-hydrazino-1,2-dihydropyrazine hydrochloride Chemical Properties |
| Melting point | 154-159°C | | Boiling point | 271.0±23.0 °C(Predicted) | | density | 1.63±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 1.27±0.20(Predicted) | | color | Very Dark Red to Brown | | InChI | 1S/C4H5ClN4/c5-3-4(9-6)8-2-1-7-3/h1-2H,6H2,(H,8,9) | | InChIKey | PUUGNIKJWZNTBK-UHFFFAOYSA-N | | SMILES | NNc1nccnc1Cl |
| Hazard Codes | Xn | | Risk Statements | 22-37/38-41 | | Safety Statements | 26-39 | | RIDADR | UN 2811 6.1 / PGIII | | WGK Germany | 3 | | HazardClass | 6.1 | | HS Code | 2933998090 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3 |
| | 3-Chloro-2-hydrazino-1,2-dihydropyrazine hydrochloride Usage And Synthesis |
| Synthesis | Step 1: 2,3-Dichloropyrazine (150 g, 1.00 mol) was dissolved in ethanol (700 mL) to which hydrazine monohydrate (124.53 g, 2.11 mmol, 85% aqueous solution) was subsequently added. The reaction mixture was heated under reflux conditions overnight. Upon completion of the reaction, the mixture was cooled and the precipitate was collected by filtration. The resulting solid was washed sequentially with water (100 mL, twice) and cold ethanol (150 mL, twice) and finally dried under reduced pressure to give 2-chloro-3-hydrazinopyrazine (140 g, 96% yield). | | References | [1] Patent: WO2016/55618, 2016, A1. Location in patent: Page/Page column 64
[2] Patent: US2014/142098, 2014, A1. Location in patent: Paragraph 0233 - 0236
[3] Patent: US2015/133447, 2015, A1. Location in patent: Paragraph 0287; 0288; 0289
[4] Patent: WO2013/39785, 2013, A2. Location in patent: Page/Page column 80; 81
[5] Patent: WO2008/130951, 2008, A1. Location in patent: Page/Page column 60 |
| | 3-Chloro-2-hydrazino-1,2-dihydropyrazine hydrochloride Preparation Products And Raw materials |
|