| Company Name: |
ChemeGen |
| Tel: |
18818260767 |
| Email: |
2625930290@qq.com |
4-[2-(2-Hydroxy-3,5-dimethylphenyl)-2-oxoethyl]piperidine-2,6-dione manufacturers
- Actiphenol
-
- $2368.00
-
2026-07-27
- CAS:526-02-3
- Purity:
- Supply Ability: 10g
|
| | 4-[2-(2-Hydroxy-3,5-dimethylphenyl)-2-oxoethyl]piperidine-2,6-dione Basic information |
| | 4-[2-(2-Hydroxy-3,5-dimethylphenyl)-2-oxoethyl]piperidine-2,6-dione Chemical Properties |
| Melting point | 200-202° | | Boiling point | 498.7±40.0 °C(Predicted) | | density | 1.232±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in DMSO; Soluble in Methanol | | form | A solid | | pka | 8.48±0.48(Predicted) |
| Hazard Codes | T | | Risk Statements | 25 | | Safety Statements | 45 | | RIDADR | UN 2811 6.1 / PGIII | | WGK Germany | 3 | | HS Code | 29419000 |
| | 4-[2-(2-Hydroxy-3,5-dimethylphenyl)-2-oxoethyl]piperidine-2,6-dione Usage And Synthesis |
| Uses | Actiphenol is an antibiotic against coxsackievirus B3 and influenza A virus (IC50s = 14.37 and 34.4 μg/mL, respectively). Actiphenol is also an aromatic ketone that exhibits weak eukaryotic translation inhibiton activity, which is found in Streptomyces species. Actiphenol can be used as a key intermediate to synthesize Cycloheximide (HY-12320)[1][2]. | | Definition | ChEBI: Actiphenol is an aromatic ketone. | | References | [1] Ji XY, et al. Synthesis and antiviral activities of synthetic glutarimide derivatives. Chem Pharm Bull (Tokyo). 2010 Nov;58(11):1436-41. DOI:10.1248/cpb.58.1436
[2] Yin M, et al. Cycloheximide and actiphenol production in Streptomyces sp. YIM56141 governed by single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase. Org Lett. 2014 Jun 6;16(11):3072-5. DOI:10.1021/ol501179w |
| | 4-[2-(2-Hydroxy-3,5-dimethylphenyl)-2-oxoethyl]piperidine-2,6-dione Preparation Products And Raw materials |
|