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Methyl 1-methyl-2-pyrroleacetate

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Methyl 1-methyl-2-pyrroleacetate manufacturers

Methyl 1-methyl-2-pyrroleacetate Basic information
Uses
Product Name:Methyl 1-methyl-2-pyrroleacetate
Synonyms:LABOTEST-BB LT00455212;METHYL 1-METHYLPYRROLE-2-ACETATE;METHYL,1-METHYL PYRROLEACETATE;METHYL 1-METHYL-2-PYRROLEACETATE;methyl 1-methylpyrrol-2-acetate;METHYL 1-METHYL-2-PYRROLEACETATE 96%;Methyl 1-methylpyrrol-2-ylacetate;1H-Pyrrole-2-acetic acid, 1-methyl-, methyl ester
CAS:51856-79-2
MF:C8H11NO2
MW:153.18
EINECS:257-478-0
Product Categories:
Mol File:51856-79-2.mol
Methyl 1-methyl-2-pyrroleacetate Structure
Methyl 1-methyl-2-pyrroleacetate Chemical Properties
Boiling point 80-85 °C2 mm Hg(lit.)
density 1.064 g/mL at 25 °C(lit.)
refractive index n20/D 1.501(lit.)
Fp 224 °F
storage temp. 2-8°C
solubility 8.3 g/L (20°C)
pka-3.42±0.70(Predicted)
form clear liquid
color Light yellow to Brown
Water Solubility 8.3 g/L (20 ºC)
InChIInChI=1S/C8H11NO2/c1-9-5-3-4-7(9)6-8(10)11-2/h3-5H,6H2,1-2H3
InChIKeyCGYVDYLHQYNGFC-UHFFFAOYSA-N
SMILESN1(C)C=CC=C1CC(OC)=O
LogP0.886 (est)
CAS DataBase Reference51856-79-2(CAS DataBase Reference)
NIST Chemistry Reference1H-Pyrrole-2-acetic acid, 1-methyl-, methyl ester(51856-79-2)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-22
Safety Statements 26-37/39
WGK Germany 3
HS Code 29333990
MSDS Information
ProviderLanguage
Methyl 1-methyl-2-pyrroleacetate English
ACROS English
SigmaAldrich English
Methyl 1-methyl-2-pyrroleacetate Usage And Synthesis
Uses1-Methyl-2-pyrroleacetic acid methyl ester can be used as a pharmaceutical synthesis intermediate.
Chemical PropertiesCLEAR ORANGE TO SLIGHTLY BROWN LIQUID
Synthesis

The intermediate 2-(1-methyl-1H-pyrrol-2-yl)-2-oxoacetic acid can be prepared from N-methylpyrrole and ethanedioyl chloride as the reaction raw materials, and 2-(1-methyl-1H-pyrrol-2-yl)acetic acid can be further reacted to prepare 2-(1-methyl-1H-pyrrol-2-yl)acetic acid, and finally esterification under the effect of p-toluenesulfonic acid to produce methyl 1-methyl-2-pyrroleacetate.

Methyl 1-methyl-2-pyrroleacetate Preparation Products And Raw materials
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