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Sigma-Aldrich |
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
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| | 2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Basic information |
| Product Name: | 2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione | | Synonyms: | 2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione;N-(3-Chloro-2-hydroxypropyl)phthalimide;Rivaroxaban Impurity 120;1H-Isoindole-1,3(2H)-dione, 2-(3-chloro-2-hydroxypropyl)-;2-(3-Chloro-2-hydroxypropyl)isoindoline-1,3-dione;SJM-SM-3-IM-4 | | CAS: | 19667-37-9 | | MF: | C11H10ClNO3 | | MW: | 239.65 | | EINECS: | | | Product Categories: | | | Mol File: | 19667-37-9.mol |  |
| | 2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Chemical Properties |
| Melting point | 95-96.5 °C | | Boiling point | 405.4±35.0 °C(Predicted) | | density | 1.444±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | pka | 13.25±0.20(Predicted) | | Appearance | White to off-white Solid |
| | 2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Usage And Synthesis |
| Uses | 2-(3-Chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione has been used in yeast biosynthesis of (S)-adrenergic β-blockers by stereoselective reduction of haloketones. It has also been used in a validated LC-MS/MS method for the determination of three genotoxic impurities in rivaroxaban drug substance. |
| | 2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Preparation Products And Raw materials |
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