| Company Name: |
Boao Pike |
| Tel: |
010-57798038 15652371397 |
| Email: |
lyn@biopike.com.cn |
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| | 5-OxoETE Receptor Polyclonal Antibody Basic information |
| | 5-OxoETE Receptor Polyclonal Antibody Chemical Properties |
| | 5-OxoETE Receptor Polyclonal Antibody Usage And Synthesis |
| Description | 5-Oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OxoETE) is a potent stimulator of chemotaxis for eosinophils and neutrophils that mediates its action via a putative G-protein coupled receptor (GPCR).1,2 The 5-OxoETE receptor couples to Gi/o to inhibit cyclic AMP production and to mobilize intracellular calcium.1,2 Northern blot analysis reveals that the receptor is highly expressed on eosinophils and neutrophils, suggesting a key role in the inflammatory response.2 In addition, the protein can also be detected in tissues such as kidney and liver.1,2 Cayman Chemical’s 5-OxoETE Receptor Polyclonal Antibody can be used in Western blot analysis (detection at 48 kDa) and immunocytochemistry. The high expression level of the receptor in leukocytes makes it the best positive control sample. When probing other tissue samples such as liver and kidney, membrane preparations or higher sensitivity detection systems may be required for visualization on immunoblot.WARNING This product is not for human or veterinary use. |
| | 5-OxoETE Receptor Polyclonal Antibody Preparation Products And Raw materials |
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