| Company Name: |
SPIRO PHARMA |
| Tel: |
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| Email: |
eric_feng1954@126.com |
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| Product Name: | YF-2 | | Synonyms: | YF-2;N-[4-chloro-3-(trifluoromethyl)phenyl]-2-[2-(dimethylamino)ethoxy]-6-ethoxybenzamide:hydrochloride;YF-2 hydrochloride | | CAS: | 1312005-62-1 | | MF: | C20H23Cl2F3N2O3 | | MW: | 467.31 | | EINECS: | | | Product Categories: | | | Mol File: | 1312005-62-1.mol |  |
| form | Solid | | color | White to light yellow |
| Uses | YF-2 is an activator of histone acetyltransferase (HAT). | | in vivo | YF-2 (20 mg/kg, 2 hours befor electric shock or 5 mg/kg, 30 min before the electric shock, i.p.) rescues the defect in contextual memory in mice, and shows no effect on contextual memory alone at 20 mg/kg in mice[1]. | | IC 50 | GCN5/PCAF: 29.04 μM (EC50); GCN5: 49.31 μM (EC50); CBP: 2.75 μM (EC50) |
| | YF-2 Preparation Products And Raw materials |
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