| Company Name: |
SPIRO PHARMA |
| Tel: |
|
| Email: |
eric_feng1954@126.com |
- YF-2
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- $50.00
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2026-06-02
- CAS:1311423-89-8
- Purity: 99.33%
- Supply Ability: 10g
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| | BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy- Basic information |
| Product Name: | BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy- | | Synonyms: | BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy-;N-[4-chloro-3-(trifluoromethyl)phenyl]-2-[2-(dimethylamino)ethoxy]-6-ethoxybenzamide;YF-2;YF 2;YF 2,HATs,inhibit,HAT,Histone Acetyltransferase,Inhibitor,YF2,YF-2;YF-2, 10 mM in DMSO | | CAS: | 1311423-89-8 | | MF: | C20H22ClF3N2O3 | | MW: | 430.85 | | EINECS: | | | Product Categories: | API | | Mol File: | 1311423-89-8.mol | ![BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy- Structure](CAS/20150408/GIF/1311423-89-8.gif) |
| | BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy- Chemical Properties |
| Boiling point | 460.8±45.0 °C(Predicted) | | density | 1.285±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml | | form | A crystalline solid | | pka | 11.75±0.70(Predicted) | | color | Light yellow to yellow |
| | BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy- Usage And Synthesis |
| Uses | YF-2 is an activator of histone acetyltransferase (HAT). | | in vivo | YF-2 (20 mg/kg, 2 hours befor electric shock or 5 mg/kg, 30 min before the electric shock, i.p.) rescues the defect in contextual memory in mice, and shows no effect on contextual memory alone at 20 mg/kg in mice[1]. | | IC 50 | GCN5/PCAF: 29.04 μM (EC50); GCN5: 49.31 μM (EC50); CBP: 2.75 μM (EC50) |
| | BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy- Preparation Products And Raw materials |
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