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Product Name:ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid CAS:57719-81-0 Purity:97.5% Package:5mg Remarks:BBP03492
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Product Name:ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid CAS:57719-81-0 Purity:95%+ Package:根据客户需求包装
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Product Name:ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid CAS:57719-81-0 Purity:97.5%HPLC Package:5mg-1g Remarks:Item No.: ALB-RS-5445
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Product Name:ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid CAS:57719-81-0 Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| | ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid Basic information |
| Product Name: | ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid | | Synonyms: | ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid;(4alpha,11beta)-11-Hydroxy-15-oxokaur-16-en-18-oic acid;Pteris diterpenoid 5F;ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid;Kaur-16-en-18-oic acid, 11-hydroxy-15-oxo-, (4α,11β)-;(1R,4S,5R,9R,10R)-11-Hydroxy-5,9-dimethyl-14-methylidene-15-oxotetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid | | CAS: | 57719-81-0 | | MF: | C20H28O4 | | MW: | 332.43 | | EINECS: | | | Product Categories: | | | Mol File: | 57719-81-0.mol |  |
| | ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid Chemical Properties |
| Boiling point | 516.6±50.0 °C(Predicted) | | density | 1.23±0.1 g/cm3(Predicted) | | pka | 4.62±0.60(Predicted) |
| | ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid Usage And Synthesis |
| Uses | ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is an anti-melanin synthesis tyrosinase inhibitor, which can be isolated from Pteris fern. ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid regulates the melanogenesis transcription factor microphthalmia-associated transcription factor (MITF). The 11α-OH, 15-oxo and 16-en moieties of ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid are key fragments that inhibit melanin synthesis. The 19-COOH moiety has been implicated in the inhibition of cytotoxicity associated with 11α-OH KA and related compounds[1]. | | References | [1] Kuroi A, et al. The Importance of 11-OH, 15-oxo, and 16-en Moieties of 11-Hydroxy-15-oxo-kaur-16-en-19-oic Acid in Its Inhibitory Activity on Melanogenesis. Skin Pharmacol Physiol. 2017;30(4):205-215. DOI:10.1159/000475471 |
| | ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid Preparation Products And Raw materials |
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