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ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid

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Products Intro: Product Name:ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid
CAS:57719-81-0
Package:1 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
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Products Intro: Product Name:ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid
CAS:57719-81-0
Purity:97.5% Package:5mg Remarks:BBP03492
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Products Intro: Product Name:ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid
CAS:57719-81-0
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Products Intro: Product Name:ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid
CAS:57719-81-0
Purity:97.5%HPLC Package:5mg-1g Remarks:Item No.: ALB-RS-5445
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Products Intro: Product Name:ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid
CAS:57719-81-0
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid Basic information
Product Name:ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid
Synonyms:ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid;(4alpha,11beta)-11-Hydroxy-15-oxokaur-16-en-18-oic acid;Pteris diterpenoid 5F;ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid;Kaur-16-en-18-oic acid, 11-hydroxy-15-oxo-, (4α,11β)-;(1R,4S,5R,9R,10R)-11-Hydroxy-5,9-dimethyl-14-methylidene-15-oxotetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid
CAS:57719-81-0
MF:C20H28O4
MW:332.43
EINECS:
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Mol File:57719-81-0.mol
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid Structure
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid Chemical Properties
Boiling point 516.6±50.0 °C(Predicted)
density 1.23±0.1 g/cm3(Predicted)
pka4.62±0.60(Predicted)
Safety Information
MSDS Information
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid Usage And Synthesis
Usesent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is an anti-melanin synthesis tyrosinase inhibitor, which can be isolated from Pteris fern. ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid regulates the melanogenesis transcription factor microphthalmia-associated transcription factor (MITF). The 11α-OH, 15-oxo and 16-en moieties of ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid are key fragments that inhibit melanin synthesis. The 19-COOH moiety has been implicated in the inhibition of cytotoxicity associated with 11α-OH KA and related compounds[1].
References[1] Kuroi A, et al. The Importance of 11-OH, 15-oxo, and 16-en Moieties of 11-Hydroxy-15-oxo-kaur-16-en-19-oic Acid in Its Inhibitory Activity on Melanogenesis. Skin Pharmacol Physiol. 2017;30(4):205-215. DOI:10.1159/000475471
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid Preparation Products And Raw materials
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