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| | Tenofovir Related Compound 4 Basic information |
| Product Name: | Tenofovir Related Compound 4 | | Synonyms: | Tenofovir alafenamide-3;TAF-IM-E1;L-Alanine, N-[[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-, 1-methylethyl ester; Tenofovir disoproxil impurity 4;sodium P-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)-N-((S)-1-isopropoxy-1-oxopropan-2-yl)phosphonamidate;Tenofovir Alafenamide Impurity 1 lithium salt;Tenofovir Related Compound 4;Desphenyl Tenofovir Alafenamide | | CAS: | 851456-00-3 | | MF: | C15H25N6O5P | | MW: | 400.38 | | EINECS: | | | Product Categories: | | | Mol File: | 851456-00-3.mol |  |
| | Tenofovir Related Compound 4 Chemical Properties |
| Boiling point | 615.0±65.0 °C(Predicted) | | density | 1.50±0.1 g/cm3(Predicted) | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 4.24±0.10(Predicted) | | color | White to Off-White | | Stability: | Hygroscopic, Unstable in Solution | | InChI | InChI=1/C15H25N6O5P/c1-9(2)26-15(22)11(4)20-27(23,24)8-25-10(3)5-21-7-19-12-13(16)17-6-18-14(12)21/h6-7,9-11H,5,8H2,1-4H3,(H2,16,17,18)(H2,20,23,24)/t10-,11+/s3 | | InChIKey | BOVSGPQGGHVIEX-WQVXQJEGNA-N | | SMILES | C(N1C=NC2=C(N=CN=C12)N)[C@@H](C)OCP(O)(=O)N[C@@H](C)C(=O)OC(C)C |&1:11,19,r| |
| | Tenofovir Related Compound 4 Usage And Synthesis |
| Uses | Desphenyl Tenofovir Alafenamide belongs to a groupof tenofovir diesters compounds, which can inhibit HIV-1 virus replication.Desphenyl Tenofovir Alafenamide can also be used to investigate the effect of oral absorption and lymphoid cell loading of GS-7340 (a prodrug of tenofovir). |
| | Tenofovir Related Compound 4 Preparation Products And Raw materials |
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