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Macitentan impurity B

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Macitentan impurity B Basic information
Product Name:Macitentan impurity B
Synonyms:Macitentan impurity B;Macitentan impurity D;Macitentan N-Despropyl-N-Ethyl Impurity;Sulfamide, N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-ethyl-;Macitentan N-Despropyl-N-Ethyl Impurity/ Macitentan N-Ethyl Analog;5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(ethylsulfamoyl)pyrimidin-4-amine;Macitentan Impurity 04;HN-MCTRCO6
CAS:441796-13-0
MF:C18H18Br2N6O4S
MW:574.25
EINECS:
Product Categories:
Mol File:441796-13-0.mol
Macitentan impurity B Structure
Macitentan impurity B Chemical Properties
Boiling point 686.7±65.0 °C(Predicted)
density 1.715±0.06 g/cm3(Predicted)
pka6.90±0.50(Predicted)
Safety Information
MSDS Information
Macitentan impurity B Usage And Synthesis
UsesN-Despropyl-N-ethyl Macitentan is an impurity of Macitentan (M105005); a dual orally active and potent endothelin receptor antagonist used for pulmonary arterial hypertension.
Macitentan impurity B Preparation Products And Raw materials
Tag:Macitentan impurity B(441796-13-0) Related Product Information
Macitidine related impurities PropylsulfaMide CarbaMic acid, N-[(propylaMino)sulfonyl]-, phenylMethyl ester 4(1H)-PyriMidinone, 5-(4-broMophenyl)-6-hydroxy- N-Propylsulfuric diamide-sodium SulfaMide, N-propyl-,(potassiuM salt)(1:1) Macitentan impurity A 5-Bromo-2-chloropyrimidine 5-(4-Bromophenyl)-4,6-dichloropyrimidine macitentan ACT 080803 Macitentan Impurity 13 Macitentan Impurity 17 Macitentan IMpurity Macitentan Impurity 2 Macitentan Impurity 14 Macitentan Impurity 10 2-(4-Bromophenyl)-propanedioic acid, 1,3-mdiethyl ester