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| | ingenol 3-benzoate Basic information |
| Product Name: | ingenol 3-benzoate | | Synonyms: | ingenol 3-benzoate;3-O-Benzoylingenol;Ingenol3-monobenzoate;1H-2,8a-Methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one, 6-(benzoyloxy)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-, (1aR,2S,5R,5aR,6S,8aS,9R,10aR)- | | CAS: | 83036-64-0 | | MF: | C27H32O6 | | MW: | 452.54 | | EINECS: | | | Product Categories: | | | Mol File: | 83036-64-0.mol |  |
| | ingenol 3-benzoate Chemical Properties |
| Boiling point | 616.4±55.0 °C(Predicted) | | density | 1.32±0.1 g/cm3(Predicted) | | pka | 11.63±0.70(Predicted) |
| | ingenol 3-benzoate Usage And Synthesis |
| Uses | Ingenol 3-monobenzoate (Ingenol 3-benzoate) is a disgust inducing agent. Ingenol 3-monobenzoate can bind to and activate PKC (Ki=0.14 nM), inhibit the gene expression of phosphoenolpyruvate carboxykinase, thereby inhibiting gluconeogenesis, and increasing blood cortisol levels, producing food aversion[1]. | | References | [1] Kronberg, et al. "Potential aversive compounds in leafy spurge for ruminants and rats." Journal of chemical ecology 21 (1995): 1387-1399. DOI:10.1007/BF02035140 |
| | ingenol 3-benzoate Preparation Products And Raw materials |
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