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| | 1,2,3,4,5,6-Hexahydro-6-methyl-azepino[4,5-b]indole hydrochloride Basic information |
| Product Name: | 1,2,3,4,5,6-Hexahydro-6-methyl-azepino[4,5-b]indole hydrochloride | | Synonyms: | PNU 22394 HYDROCHLORIDE;Azepino[4,5-b]indole, 1,2,3,4,5,6-hexahydro-6-methyl-;PNU22394 HCl;1,2,3,4,5,6-Hexahydro-6-methyl-azepino[4,5-b]indole hydrochloride | | CAS: | 15923-78-1 | | MF: | C13H16N2 | | MW: | 200.28 | | EINECS: | | | Product Categories: | Serotonin receptor | | Mol File: | 15923-78-1.mol | ![1,2,3,4,5,6-Hexahydro-6-methyl-azepino[4,5-b]indole hydrochloride Structure](CAS/GIF/15923-78-1.gif) |
| | 1,2,3,4,5,6-Hexahydro-6-methyl-azepino[4,5-b]indole hydrochloride Chemical Properties |
| Boiling point | 383.0±32.0 °C(Predicted) | | density | 1.17±0.1 g/cm3(Predicted) | | storage temp. | Desiccate at +4°C | | pka | 10.73±0.20(Predicted) |
| | 1,2,3,4,5,6-Hexahydro-6-methyl-azepino[4,5-b]indole hydrochloride Usage And Synthesis |
| Uses | PNU 22394 is a potent SR-2C agonist and partial SR-2A/SR-2B agonist. Central nervous system sedative. A tryptamine derivative which has hyperthermic effects. | | Biological Activity | Potent 5-HT 2C agonist and partial 5-HT 2A /5-HT 2B agonist. Non-selective between 5-HT 2 receptor subtypes (K i values are 18, 18 and 66 nM for human recombinant 5-HT 2C , 5-HT 2A and 5-HT 2B receptors respectively). Reduces food intake in rats following subcutaneous administration and displays anorexigenic effects in humans. |
| | 1,2,3,4,5,6-Hexahydro-6-methyl-azepino[4,5-b]indole hydrochloride Preparation Products And Raw materials |
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