|
|
| | Muscle form hexokinase Basic information |
| Product Name: | Muscle form hexokinase | | Synonyms: | Monoclonal Anti-HK2 antibody produced in mouse;HK II;HXK2;fi17h06;wu:fi09d05;HOOK2;DKFZp686M1669;Hexokinase type II | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Muscle form hexokinase Structure]() |
| | Muscle form hexokinase Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous glycerol solution | | Specific Activity | 3-4units/mL |
| WGK Germany | 1 | | Storage Class | 10 - Combustible liquids |
| | Muscle form hexokinase Usage And Synthesis |
| Uses | Hexokinase 2 (HK2) is a glycolytic enzyme that is crucial for the Warburg effect, which is the increased rate of glycolysis seen in rapidly growing cancer cells. HK2 may be used in cancer research to study human glioblastoma multiforme (GBM), which is the most common malignant brain tumor . HK2 may be a potential therapeutic target for breast cancer as HK2 overexpression is associated with metastasis to the brain . | | General Description | Hexokinase 2 is the predominant form found in skeletal muscle. | | Biochem/physiol Actions | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase 2 is involved in glucose metabolism and apoptosis . |
| | Muscle form hexokinase Preparation Products And Raw materials |
|