bHLHb40 manufacturers
- HE-S2
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- $1520.00
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2026-07-27
- CAS:2939851-67-7
- Purity:
- Supply Ability: 10g
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| | bHLHb40 Basic information |
| Product Name: | bHLHb40 | | Synonyms: | ANTI-HES2 antibody produced in mouse;bHLHb40;HES2;Benzenemethanaminium, 4-[[2-amino-4-(butylamino)pyrido[3,2-d]pyrimidin-6-yl]methyl]-N,N-dimethyl-N-[[4-[[[(2R)-2-[(5-nitro-2-pyridinyl)dithio]propoxy]carbonyl]amino]phenyl]methyl]-, formate (1:1) | | CAS: | 2939851-67-7 | | MF: | C37H44N9O4S2.CHO2 | | MW: | 787.95 | | EINECS: | | | Product Categories: | | | Mol File: | 2939851-67-7.mol |  |
| | bHLHb40 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | mouse |
| Storage Class | 10 - Combustible liquids |
| | bHLHb40 Usage And Synthesis |
| Uses | HE-S2 is an antibody-drug conjugate triggering a potent antitumor immune response. HE-S2 acts by blocking the PD-1/PD-L1 interaction and activating the Toll-like receptor 7/8 (TLR7/8) signaling pathway. HE-S2 has remarkable antitumor activity[1]. | | References | [1] He L, et al. Immune Modulating Antibody-Drug Conjugate (IM-ADC) for Cancer Immunotherapy. J Med Chem. 2021;64(21):15716-15726. DOI:10.1021/acs.jmedchem.1c00961 |
| | bHLHb40 Preparation Products And Raw materials |
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